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Immunoadsorption

In most cases, kidney damage and function decline is related with active inflammatory response within kidneys. Due inflammatory response could be caused by Inflammatory factors that circulate to kidneys with blood flow, or these deposited immune complexes like with the cases of IgA Nephropathy or Lupus Nephritis, etc.

Immunoadsorption is one of the dominant blood purification technologies, aiming at cleaning out antibodies, immune complexes and some other pathogentic factors . Different from many other blood purification technologies, Immunoadsorption allows not only a more specific but also a more effective clearance of circulating harmful substances in the blood.

In clinic, the basic operation procedure of Immunoadsorption can be described as following:

1. Blood circulated out of body in to the extracorporeal system. During this procedure, anticoagulation measures are needed.

2. Removing plasma that contains inflammatory factors out of blood with the help of Plasma-Flow.

3. Leading plasma to a medical machine in which pathogentic factors are reabsorbed by adsorbent in selective way.

4, Purified blood is returned to patient's body. And now, the plasma is healthy and contains no substances like inflammatory factors, immune complexes, etc.

Immunoadsorption shows great treatment effects in the following several aspects:

1. Removal of pathologenic factors

As a matter of fact, many diseases can be attributed to circulating pathologenic factors like autoimmune antibodies, circulating immune complexes, tumor necrosis factors, interleukin, low density lipoprotein, circulating toxins and endotoxin and so on.

2. Removal of anaphylatoxin

Removal of anaphylatoxin is very helpful for delaying inflammatory reaction and influence of cell factor.

3. Regulating immune system

Immunoadsorption helps to regulate patient's immune system by decreasing the synthesis of interleukin-1 and interleukin-6 as well as reducing the release of inflammatory mediators.

In clinic, Immunoadsorption can be used to treat many diseases like kidney diseases, organ transplantation, blood diseases, nerve system diseases and rheumatic disease. As Immunoadsorption shows quick and obvious treatment effects in regulating immune system and removing pathologenic factors in blood, among its indicatons, Immunoadsorption is especially effective in treating SLE (Systemic Lupus Erythematosus), a kind of autoimmune disease.

Although Immunoadsorption plays an important role in purifying blood, its treatment effects are temporary, so it is usually used together with some oral medicines. Besides, as improper application of Immunoadsorption may bring side effects, so while appling Immunoadsorption, a close observation is necessary.

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